Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		0.560 Biomarker disease RGD Delayed minocycline inhibits ischemia-activated matrix metalloproteinases 2 and 9 after experimental stroke. 16846501 2006
Entrez Id: 3627
Gene Symbol: CXCL10
CXCL10 		0.510 Biomarker disease RGD Minocycline modulates chemokine receptors but not interleukin-10 mRNA expression in hypoxic-ischemic neonatal rat brain. 17549754 2007
Entrez Id: 3606
Gene Symbol: IL18
IL18 		0.510 Biomarker disease RGD In this study, the authors analyzed the expression pattern of interleukin-18, -1beta, and caspase-1 in focal brain ischemia induced in rats either by permanent middle cerebral artery occlusion or by photothrombosis of cortical microvessels. 11807395 2002
Entrez Id: 3605
Gene Symbol: IL17A
IL17A 		0.510 Biomarker disease RGD Expression of interleukin-17 in ischemic brain tissue. 16305645 2005
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		0.510 Biomarker disease RGD [Influence of JDTL injection on inflammatory factors in rat experimental cerebral ischemia]. 19260320 2008
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		0.510 Biomarker disease RGD Evidence of HIF-1 functional binding activity to caspase-3 promoter after photothrombotic cerebral ischemia. 17101276 2007
Entrez Id: 847
Gene Symbol: CAT
CAT 		0.510 Biomarker disease RGD Antioxidant activities of Dracocephalum tanguticum maxim extract and its up-regulation on the expression of neurotrophic factors in a rat model of permanent focal cerebral ischemia. 21213399 2011
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		0.510 Therapeutic disease RGD Desferoxamine preconditioning protects against cerebral ischemia in rats by inducing expressions of hypoxia inducible factor 1 alpha and erythropoietin. 18369388 2008
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A 		0.500 Biomarker disease RGD TNFR1 mediates increased neuronal membrane EAAT3 expression after in vivo cerebral ischemic preconditioning. 16442237 2006
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.500 Biomarker disease RGD Hydrogen supplemented air inhalation reduces changes of prooxidant enzyme and gap junction protein levels after transient global cerebral ischemia in the rat hippocampus. 21718970 2011
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.500 Biomarker disease RGD Cyclooxygenase-2 mRNA expression is associated with c-fos mRNA expression and transient water ADC reduction detected with diffusion MRI during acute focal ischemia in rats. 12535784 2003
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		0.240 Biomarker disease RGD Transient cerebral ischemia induces site-specific hyperphosphorylation of tau protein. 15353210 2004
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		0.230 Biomarker disease RGD Insulin-like growth factor-1 is an endogenous mediator of focal ischemia-induced neural progenitor proliferation. 16882007 2006
Entrez Id: 177
Gene Symbol: AGER
AGER 		0.230 Biomarker disease RGD RAGE is expressed in pyramidal cells of the hippocampus following moderate hypoxic-ischemic brain injury in rats. 12618340 2003
Entrez Id: 6546
Gene Symbol: SLC8A1
SLC8A1 		0.220 Biomarker disease RGD NCX1 and NCX3: two new effectors of delayed preconditioning in brain ischemia. 22036625 2012
Entrez Id: 6285
Gene Symbol: S100B
S100B 		0.220 Biomarker disease RGD Peripheral administration of human adrenomedullin and its binding protein attenuates stroke-induced apoptosis and brain injury in rats. 21695352 2012
Entrez Id: 6546
Gene Symbol: SLC8A1
SLC8A1 		0.220 Biomarker disease RGD Altered gene expression of Na+/Ca2+ exchanger isoforms NCX1, NCX2 and NCX3 in chronic ischemic rat brain. 12377375 2002
Entrez Id: 2697
Gene Symbol: GJA1
GJA1 		0.220 Biomarker disease RGD Hydrogen supplemented air inhalation reduces changes of prooxidant enzyme and gap junction protein levels after transient global cerebral ischemia in the rat hippocampus. 21718970 2011
Entrez Id: 6546
Gene Symbol: SLC8A1
SLC8A1 		0.220 Biomarker disease RGD Altered expression of sodium transporters in ischemic penumbra after focal cerebral ischemia in rats. 17662498 2007
Entrez Id: 199
Gene Symbol: AIF1
AIF1 		0.220 Biomarker disease RGD Time dependent changes of striatal interneurons after focal cerebral ischemia in rats. 18301954 2008
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1 		0.210 Therapeutic disease RGD Combination of Ligusticum chuanxiong and Radix Paeoniae ameliorate focal cerebral ischemic in MCAO rats via endoplasmic reticulum stress-dependent apoptotic signaling pathway. 27108052 2016
Entrez Id: 4842
Gene Symbol: NOS1
NOS1 		0.210 Biomarker disease RGD Hydrogen supplemented air inhalation reduces changes of prooxidant enzyme and gap junction protein levels after transient global cerebral ischemia in the rat hippocampus. 21718970 2011
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.210 Biomarker disease RGD Estradiol modulates bcl-2 in cerebral ischemia: a potential role for estrogen receptors. 10414967 1999
Entrez Id: 6529
Gene Symbol: SLC6A1
SLC6A1 		0.210 Biomarker disease RGD Sequential release of GABA by exocytosis and reversed uptake leads to neuronal swelling in simulated ischemia of hippocampal slices. 15084665 2004
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		0.210 Therapeutic disease RGD Lentiviral-mediated delivery of Bcl-2 or GDNF protects against excitotoxicity in the rat hippocampus. 15585409 2005